Placenta Messages to the Mother

Placenta messages to the mother: not just debris.

Preeclampsia is a major pregnancy complication, affecting 5% of all pregnancies, that is responsible for 50 000 maternal deaths annually. The only cure for preeclampsia is delivery, which, in early onset cases, will be a premature one. The adverse acute and chronic clinical impact on the mother and the child may be severe; the cost to society is immense. Preeclamptic women are at increased risk...

I-7: Maternal Signalling to the Placenta

Background: Though it is well established that maternal blood-borne signals influence highly the growth of the placenta, the mechanisms are not known. In vitro trophoblast culture models are limited by an inability to reconstruct the polarised bilayer of the human hemochorial placenta. We have used a first trimester villous tissue explant system to investigate how growth factors interact with p...

The Selectivity of the Human Placenta in the Transfer of Plasma Proteins from Mother to Fetus.

Making Sense of Hurtful Mother-in-law Messages: Applying Attribution Theory to the In-Law Triad

This study focused on hurtful messages daughters-in-law (DILs, N = 132) reported receiving from mothers-in-law (MILs). Results reveal various hurtful message types: underand overinvolvement, personal attacks, and hurt communicated to or through a third party. Grounded in attribution theory, we examined DILs’ attributions for MILs’ hurtful messages and their perceived agreement with their husban...

Mother-to-infant transmission of HIV-1: the placenta fights back.